PXD078120 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Intact Protein TMT Labeling and 2D High-pH/Low-pH RP/RPLC-MS/MS |
| Description | Optimization of intact protein TMT labeling and multidimensional high-pH/low-pH RP/RPLC-MS/MS. Application of this platform for quantification of proteoform-level abundance changes as a result of staursporine treatment in HeLa cells. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-08-13 |
| AnnouncementXML | Submission_2026-08-13_04:06:26.419.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Kellye Sutton |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | TMT6plex-126 reporter+balance reagent acylated residue; iodoacetamide derivatized residue |
| Instrument | orbitrap |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2026-05-07 08:26:23 | ID requested | |
| ⏵ 1 | 2026-08-13 04:06:27 | announced | |
Publication List
| 10.1016/j.aca.2026.345846; |
| Guo Y, Chowdhury T, Galie WP, Cupp-Sutton KA, Zhao Z, Solenberger A, Yu D, Wu S, Deep intact proteoform quantification of low-microgram-scale proteome by tandem mass tag labeling and online 2D high-pH/low-pH RPLC top-down analysis. Anal Chim Acta, 1418():345846(2026) [pubmed] |
Keyword List
| submitter keyword: TMT labeling,Top-down proteomics, multidimensional LC-MS |
Contact List
| Si Wu |
|---|
| contact affiliation | The University of Alabama |
| contact email | swu49@ua.edu |
| lab head | |
| Kellye Sutton |
|---|
| contact affiliation | University of Alabama |
| contact email | kasutton3@ua.edu |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/08/PXD078120 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD078120
- Label: PRIDE project
- Name: Intact Protein TMT Labeling and 2D High-pH/Low-pH RP/RPLC-MS/MS
