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PXD078089-1

PXD078089 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleMolecular Classification of Pancreatic Intraductal Tumors Based on DIA-MS/MS-Enabled Quantitative Proteomics
DescriptionData-independent acquisition tandem mass spectrometry (DIA-MS/MS) quantitative proteomics was performed on formalin-fixed paraffin-embedded (FFPE) tissue samples, including IPMN-GNAS wild-type (IPMN-WT), IPMN-GNAS mutant (IPMN-GNASâș), and ITPN tissues. All samples were processed with a customized and optimized FFPE protein pretreatment workflow. The raw DIA mass spectrometry files were generated to explore differentially expressed proteins, distinct proteomic profiles, and altered signaling pathways among three tissue subtypes. The acquired MS data support the quantitative analysis of stably dysregulated proteins, bioinformatics enrichment analysis, and subsequent histological validation of key biomarker proteins in pancreatic precursor neoplasms.
HostingRepositoryiProX
AnnounceDate2026-05-01
AnnouncementXMLSubmission_2026-05-06_18:01:17.067.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterLinru Shen
SpeciesList scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentZenoTOF 7600
Dataset History
RevisionDatetimeStatusChangeLog Entry
02026-05-06 18:00:29ID requested
⏵ 12026-05-06 18:01:18announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: pancreatic ductal adenocarcinoma, IPMN, ITPN, DIA-MS/MS
Contact List
Lei Fang
contact affiliationNanjing University
contact email502024350026@smail.nju.edu.cn
lab head
Linru Shen
contact affiliationNanjing University
contact email2959042161@qq.com
dataset submitter
Full Dataset Link List
iProX dataset URI

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