PXD078052 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Proteomic analysis of 3T3 murine fibroblast used as feeder-layer |
| Description | 3T3 murine embryonic fibroblasts are used as feeder layers to support the proliferative potential of human primary keratinocytes during in vitro expansion for cell and gene therapy applications. To identify signals mediating this function, we analyzed fibroblast protein content using mass spectrometry. We compared the proteome of lethally irradiated fibroblasts used as feeder layers in two conditions: standard quality (SQ-FL) and low quality (LQ-FL) fibroblasts. Our findings highlight differences in extracellular matrix components between the two conditions |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-05-18 |
| AnnouncementXML | Submission_2026-05-18_04:35:18.586.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Antonio Marino |
| SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: NEWT:10090; |
| ModificationList | mono N-acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue |
| Instrument | Orbitrap Ascend |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2026-05-06 01:52:59 | ID requested | |
| ⏵ 1 | 2026-05-18 04:35:19 | announced | |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: feeder-layer,fibroblast, skin expansion |
Contact List
| Elena Enzo |
|---|
| contact affiliation | Centre for Regenerative Medicine “Stefano Ferrari”, University of Modena and Reggio Emilia, Modena, Italy |
| contact email | elena.enzo@unimore.it |
| lab head | |
| Antonio Marino |
|---|
| contact affiliation | Proteomics Research Infrastructure (PRI) - UCPH |
| contact email | antonio.marino@pri.ku.dk |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/05/PXD078052 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD078052
- Label: PRIDE project
- Name: Proteomic analysis of 3T3 murine fibroblast used as feeder-layer
