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PXD078043-1

PXD078043 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleIdentification of the direct molecular target of sanguinarine in bladder cancer cells
DescriptionSanguinarine possesses anticancer, antioxidant activities; however, its direct target(s) and mechanism of action have long remained unclear, limiting its translational and clinical application. Here, we employed limited proteolysis-coupled mass spectrometry (LiP-MS) to identify its direct target(s) in the T24 bladder cancer cell line, thereby providing a theoretical basis for further clinical development.
HostingRepositoryiProX
AnnounceDate2026-05-01
AnnouncementXMLSubmission_2026-05-06_01:21:04.308.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterChuanzan Zhou
SpeciesList scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive HF-X
Dataset History
RevisionDatetimeStatusChangeLog Entry
02026-05-06 01:20:40ID requested
12026-05-06 01:21:05announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Bladder cancer,LiP-MS,T24,Sanguinarine
Contact List
Dahong Zhang
contact affiliationZhejiang Provincial People's Hospital
contact emailZhangdahong666@163.com
lab head
Chuanzan Zhou
contact affiliationZhejiang provinces peoples hospital
contact emailzhouchuanzan@hmc.edu.cn
dataset submitter
Full Dataset Link List
iProX dataset URI