PXD078006 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | HPLC-MS/MS analysis of the S-monooxygenated S-Trp (O=S-Trp) bearing peptide in EcKatG S-Trp105 |
| Description | A sulfur-containing analog of tryptophan, thiotryptophan (3-benzothienyl-L-alanine, S-Trp), was genetically incorporated into EcKatG to replace the MYW-forming tryptophan, W105. The S-Trp-bearing peptide was isolated using trypsin digestion followed by HPLC separation. Tandem mass spectrometry (MS/MS) was then performed to verify the substitution. The final results demonstrated that S-Trp was successfully incorporated and subsequently underwent S-monooxygenation, yielding O=S-Trp. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-05-13 |
| AnnouncementXML | Submission_2026-05-13_08:49:06.771.xml |
| DigitalObjectIdentifier | https://doi.org/10.6019/PXD078006 |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Supported dataset by repository |
| PrimarySubmitter | Ran Duan Duan |
| SpeciesList | scientific name: Escherichia coli; NCBI TaxID: NEWT:562; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | maXis |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2026-05-05 06:25:23 | ID requested | |
| ⏵ 1 | 2026-05-13 08:49:07 | announced | |
Publication List
Keyword List
| submitter keyword: catalase-peroxidase, Non-canical amino acid,KatG |
Contact List
| Aimin Liu |
|---|
| contact affiliation | Professor Emeritus Department of Chemistry The University of Texas at San Antonio Effective July 1, 2026: Johnson Foundation Professor of Chemical Enzymology Department of Biochemistry and Biophysics, Perelman School of Medicine Department of Chemistry, School of Arts and Sciences University of Pennsylvania, Philadelphia, PA 19104 |
| contact email | aimin.liu@utsa.edu |
| lab head | |
| Ran Duan Duan |
|---|
| contact affiliation | University of Texas at San Antonio |
| contact email | ran.duan@utsa.edu |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
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| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD078006
- Label: PRIDE project
- Name: HPLC-MS/MS analysis of the S-monooxygenated S-Trp (O=S-Trp) bearing peptide in EcKatG S-Trp105
