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PXD077983-1

PXD077983 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleCarbamylome and acetylome analyses of MIN6 insulin-producing cells treated with pro-inflammatory cytokines
DescriptionMIN6 cells were treated for 15 min, 2 hr, and 24 hr with the combination of pro-inflammatory cytokines IFN-g, IL-1b and TNFa. Samples were digested with trypsin, labeled with TMT, fractionated by high pH reverse phase chromatography, and acetylated and carbamylated peptides were simultaneously captured with anti-acetyllysine antibodies before being analyzed by LC-MS/MS. Data was searched with MS-GF+ using PNNL's DMS processing pipeline.
HostingRepositoryMassIVE
AnnounceDate2026-06-03
AnnouncementXMLSubmission_2026-06-03_12:09:05.412.xml
DigitalObjectIdentifier
ReviewLevelNon peer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterMatthew Monroe
SpeciesList scientific name: Mus musculus; common name: house mouse; NCBI TaxID: 10090;
ModificationListOxidation; Carbamidomethyl; Deamidated; Acetyl; Carbamyl; TMTpro
InstrumentQ Exactive HF-X
Dataset History
RevisionDatetimeStatusChangeLog Entry
02026-05-04 10:24:52ID requested
12026-06-03 12:09:05announced
Publication List
no publication
Keyword List
submitter keyword: type 1 diabetes, carbamylation, acetylation, islets, inflammation, autoimmune disease, DatasetType:Proteomics
Contact List
Ernesto Nakayasu
contact affiliationPacific Northwest National Laboratory
contact emailernesto.nakayasu@pnnl.gov
lab head
Matthew Monroe
contact affiliationPacific Northwest National Laboratory
contact emailmatthew.monroe@pnnl.gov
dataset submitter
Full Dataset Link List
MassIVE dataset URI
Dataset FTP location
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