⮝ Full datasets listing
PXD077673-1
PXD077673 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | PMS2 inhibitor NP1867 cysteinome adduction by cell-based proteomincs |
| Description | MMR protein PMS2 is a druggable target. Discovery and characterisation of first-in-class small molecule MMR pathway modulator NP1867. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-04-28 |
| AnnouncementXML | Submission_2026-04-28_14:40:37.145.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Alexia Hervieu |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2026-04-27 14:36:54 | ID requested | |
| ⏵ 1 | 2026-04-28 14:40:37 | announced |
Publication List
| 10.1158/2159-8290.cd-26-0003; |
| Blagg J, Riou P, Hervieu A, Piumatti E, Rodriguez-Plata MT, Battuello P, Peall A, Amodio V, Vitiello PP, Nightingale DJH, Bago R, Tongue P, Slater T, Parmar K, Patel P, Rodr, í, guez Gonz, á, lez J, Clark DE, Langley GW, Nichols C, Guarne A, Winship PCM, Baker M, Drysdale M, Germano G, Bardelli A, Pharmacological inhibition of PMS2 induces MMR deficiency and response to immune checkpoint blockade. Cancer Discov, ():(2026) [pubmed] |
Keyword List
| submitter keyword: None |
Contact List
| Rob Howes, | |
|---|---|
| contact affiliation | Discovery | Charles River Chesterford Research Park, CB10 1XL, United Kingdom P: +44 1799 533 500 |
| contact email | rob.howes@crl.com |
| lab head | |
| Alexia Hervieu | |
| contact affiliation | NeoPhore Ltd. |
| contact email | alexia.hervieu@neophore.com |
| dataset submitter | |
Full Dataset Link List
| Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/04/PXD077673 |
| PRIDE project URI |
Repository Record List
[ + ]
