PXD077611 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Membrane Enriched Subcellular Proteomic Analysis of KBU2046 Treated PC3 Prostate Cancer Cells |
| Description | This study investigates localized protein networks at the cell boundary of human prostate cancer PC3 cells following a 72 hour exposure to the selective motility inhibitor KBU2046. Membrane fractions were isolated using a commercial extraction kit to evaluate spatial dynamics at the cell periphery. Extracted surface proteins were then chemically labeled with Tandem Mass Tags to enable multiplexed quantitative proteomic analysis of the dynamic surfaceome. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-09-03 |
| AnnouncementXML | Submission_2026-09-03_12:30:25.129.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Weining Chen |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | monohydroxylated residue; iodoacetamide derivatized residue |
| Instrument | Orbitrap Exploris 480 |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
| 0 | 2026-04-25 17:26:36 | ID requested | |
| ⏵ 1 | 2026-09-03 12:30:25 | announced | |
| 2 | 2026-09-03 12:31:58 | announced | 2026-09-03: Updated project metadata. |
Publication List
Keyword List
Contact List
| Raymond Bergan |
| contact affiliation | Director Stony Brook Cancer Center |
| contact email | Raymond.Bergan@stonybrookmedicine.edu |
| lab head | |
| Weining Chen |
| contact affiliation | University of Nebraska Medical Center |
| contact email | wchen@unmc.edu |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/09/PXD077611 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD077611
- Label: PRIDE project
- Name: Membrane Enriched Subcellular Proteomic Analysis of KBU2046 Treated PC3 Prostate Cancer Cells