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PXD077552-1

PXD077552 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleDrug repurposing: antimicrobial mechanism of T-2307 against S. aureus
DescriptionWith the growing antibiotic resistance of Staphylococcus aureus, it is urgent to discover new antimicrobials to solve this problem. By bacterial growth based high-throughput screening, we identified FDA-approved drug T-2307 with effective antimicrobial activity against S. aureus. This study aims to explore the model of action of the compound by proteomics analysis and other microbiological methods. The data would provide us information about the regulated proteins, and hence help us further study the underlying antimicrobial mechanisms by the compound.
HostingRepositoryiProX
AnnounceDate2026-04-23
AnnouncementXMLSubmission_2026-04-23_18:49:36.823.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterPengfei She
SpeciesList scientific name: Staphylococcus aureus; NCBI TaxID: 1280;
ModificationListNo PTMs are included in the dataset
InstrumentOrbitrap Astral
Dataset History
RevisionDatetimeStatusChangeLog Entry
02026-04-23 18:49:20ID requested
12026-04-23 18:49:37announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: S. aureus, antimicrobial, resistance
Contact List
Yong Wu
contact affiliationThe Third Xiangya Hospital of Central South University
contact emailwuyong_zn@csu.edu.cn
lab head
Pengfei She
contact affiliationThe Third Xiangya Hospital of Central South University
contact email761420352@qq.com
dataset submitter
Full Dataset Link List
iProX dataset URI