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PXD077386-1

PXD077386 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleAmplifying Tumor Antigen Presentations from Intratumorally Entrapped Dendritic Cells.
Descriptionď‚·This study aims to characterize the proteomic changes of extracellular vesicles (DEVs) released by ginseng vesicles (GEN) or IGNITE-treated mouse bone marrow-derived dendritic cells (BMDCs) using proteomics technology. DEVs were secreted by primary BMDCs . After 24-hour treatment of mouse bone marrow-derived dendritic cells (BMDCs) with either untreated material or ginseng vesicles (GEN) or IGNITE, the released extracellular vesicles (DEVs) under different treatments were collected. Proteins were extracted and subjected to enzymatic digestion, labeled with TMTpro/TMT 16-linked/TMT 10-linked reagents (select according to the actual kit), and analyzed by liquid chromatography-tandem mass spectrometry (LC-MS/MS).The resulting datasets enable the identification and semi-quantitative analysis of differentially expressed proteins and related pathways.
HostingRepositoryPRIDE
AnnounceDate2026-06-01
AnnouncementXMLSubmission_2026-05-31_19:37:17.522.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterZhiwang Li
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: NEWT:10090;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02026-04-20 10:40:56ID requested
12026-05-31 19:37:18announced
Publication List
10.1038/S41565-026-02204-2;
Keyword List
submitter keyword: Dendritic Cells,Antigen Presentation,tumor immunotherapy,Extracellular vesicles
Contact List
Jingjing Zhang
contact affiliationState Key Laboratory of Organic Electronics and Information Displays Jiangsu Key Laboratory of Smart Biomaterials and Theranostic Technology, Nanjing University of Posts and Telecommunications, Nanjing 210023, China;
contact emailiamxgding@njupt.edu.cn
lab head
Zhiwang Li
contact affiliationCosmos Wisdom Institute of Excellence and Innovation
contact emaillizhiwang@cwmda.com
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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