PXD077377 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Comparative proteomics analysis of wild-type vs Caj1 overexpressing cells |
| Description | This study presents a comparative label-free quantitative proteomic analysis of Saccharomyces cerevisiae wild-type cells carrying an empty vector (WT + EV), cells overexpressing Caj1 under the TEF1 promoter (TEF1-Caj1) and Caj1 deletion cells carrying an empty vector (del Caj1 + EV) . Caj1 is a cytosolic chaperone, and its overexpression is hypothesized to influence cellular protein homeostasis. Whole-cell lysates were prepared from the indicated strains and subjected to LC–MS/MS analysis. The aim of this study is to identify differentially abundant proteins associated with Caj1 overexpression and to understand its impact on global proteome remodeling. The dataset provides insights into pathways potentially regulated by Caj1 and contributes to understanding chaperone-mediated proteostasis in yeast. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-04-28 |
| AnnouncementXML | Submission_2026-04-28_10:05:32.543.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Preeti Sagarika |
| SpeciesList | scientific name: Saccharomyces cerevisiae (Baker's yeast); NCBI TaxID: NEWT:4932; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2026-04-20 04:48:01 | ID requested | |
| ⏵ 1 | 2026-04-28 10:05:33 | announced | |
Publication List
Keyword List
| submitter keyword: Caj1 , Molecular chaperones |
Contact List
| Chandan Sahi |
|---|
| contact affiliation | Associate Professor Department of Biological Sciences Indian Institute of Science Education and Research-Bhopal MP, India |
| contact email | sahi@iiserb.ac.in |
| lab head | |
| Preeti Sagarika |
|---|
| contact affiliation | JNCASR |
| contact email | preetisagarika21@gmail.com |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/04/PXD077377 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD077377
- Label: PRIDE project
- Name: Comparative proteomics analysis of wild-type vs Caj1 overexpressing cells
