PXD077347 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | H3pT11 regulates histone homeostasis and replication-coupled nucleosome assembly |
| Description | newly synthesized H3 is phosphorylated at T11 by the CPC complex, licensing Asf1 binding and nuclear import; upon nuclear entry, H3pT11 facilitates Rtt109-catalyzed H3K56 acetylation, which antagonizes Hat1 and promotes nucleosome assembly by CAF-1 and Rtt106 16; subsequently, Rtt101-mediated H3K122 ubiquitination destabilizes the Asf1-H3/H4 interaction, enabling dimer transfer from Asf1 to CAF-1 |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-08-05 |
| AnnouncementXML | Submission_2026-08-04_22:39:39.375.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Yu Qi |
| SpeciesList | scientific name: Saccharomyces cerevisiae (Baker's yeast); NCBI TaxID: NEWT:4932; |
| ModificationList | phosphorylated residue; acetylated residue |
| Instrument | Q Exactive HF |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
| 0 | 2026-04-19 09:51:34 | ID requested | |
| ⏵ 1 | 2026-08-04 22:39:39 | announced | |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: H3K79me3 H3T11 phosphorylation histone homeostasis |
Contact List
| Yu qi |
| contact affiliation | School of Life Sciences, Hubei University, Wuhan, Hubei 430062, China |
| contact email | yuqi195316@outlook.com |
| lab head | |
| Yu Qi |
| contact affiliation | hubei university |
| contact email | yuqi195316@outlook.com |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/08/PXD077347 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD077347
- Label: PRIDE project
- Name: H3pT11 regulates histone homeostasis and replication-coupled nucleosome assembly