⮝ Full datasets listing
PXD077062-1
PXD077062 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Proteomics of AC-16 cells treated with DOX |
| Description | Doxorubicin (DOX) is a potent chemotherapeutic agent, but its clinical use is limited by dose-dependent cardiotoxicity. To elucidate the molecular mechanisms underlying DOX-induced cardiomyopathy, we performed quantitative proteomic analysis on DOX-treated human AC-16 cardiomyocytes. The treatment group comprised AC-16 cells exposed to 0.2 µM DOX for 48 hours, with solvent-treated cells serving as the control. |
| HostingRepository | iProX |
| AnnounceDate | 2026-04-13 |
| AnnouncementXML | Submission_2026-04-13_00:14:32.010.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Jinyu Zhao |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Orbitrap Astral |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2026-04-13 00:13:56 | ID requested | |
| ⏵ 1 | 2026-04-13 00:14:32 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: DOX,AC-16 cells,proteomics |
Contact List
| Xianwei Wang | |
|---|---|
| contact affiliation | Henan Key Laboratory of Medical Tissue Regeneration |
| contact email | Wangxianwei1116@126.com |
| lab head | |
| Jinyu Zhao | |
| contact affiliation | Henan Key Laboratory of Medical Tissue Regeneration |
| contact email | jinyuzhao123@126.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
