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PXD077028-1

PXD077028 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleFLAG-IP, FLAG-FBXO7 samples with domain deletions of FBXO7 variants, with or without FBXO7
DescriptionTriplicate FLAG-Immunoprecipitations of FLAG-tagged FBXO7 constructs (full length (1-522), ∆N (169-522), ∆C (1-406), and ∆N∆C (169-406)) overexpressed in FBXO7-/- PSMF1-/- HEK293T cells. FBXO7∆N∆C co-overexpressed with full length PI31(1-271) is also included. Parental cells lacking tagged FBXO7 are included as a negative control for non-specific binding in the IP. Identities of each sample and their layout by TMT channel are included as table.
HostingRepositoryPRIDE
AnnounceDate2026-06-22
AnnouncementXMLSubmission_2026-06-22_11:59:13.867.xml
DigitalObjectIdentifierhttps://doi.org/10.6019/PXD077028
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterEllen Goodall
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationListTMT6plex-126 reporter+balance reagent acylated residue
InstrumentOrbitrap Fusion Lumos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02026-04-10 21:51:12ID requested
12026-06-22 11:59:14announced
Publication List
10.64898/2026.05.28.728263;
10.6019/PXD077028;
Keyword List
submitter keyword: Parkinson's Disease, Human, IP-MS,FBXO7
Contact List
J. Wade Harper
contact affiliationHarvard Medical School Cell Biology Department
contact emailwade_harper@hms.harvard.edu
lab head
Ellen Goodall
contact affiliationHarvard Medical School
contact emailellen_goodall@hms.harvard.edu
dataset submitter
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Dataset FTP location
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PRIDE project URI
Repository Record List
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