PXD077016 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | HAPI31-IP-MS, containing PI31 truncations and Parkinson's associated variants, with or without FBXO7 |
| Description | Triplicate HA-Immunoprecipitations of HA-tagged PI31 variants including full length (1-271), FP domain (1-151) and Parkinson's associated sequence variants, L53M, L228V, R231X(1-230), R242G, R242C, overexpressed in FBXO7-/- PSMF1-/- HEK293T cells co-overexpressed with full length FBXO7(1-522), or without FBXO7 (empty vector). Wild type HEK293T samples without tagged bait represent a negative control IP. Identities of each sample are included in separate associated table. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-06-22 |
| AnnouncementXML | Submission_2026-06-22_12:00:32.020.xml |
| DigitalObjectIdentifier | https://doi.org/10.6019/PXD077016 |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Supported dataset by repository |
| PrimarySubmitter | Ellen Goodall |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | TMT6plex-126 reporter+balance reagent acylated residue |
| Instrument | Orbitrap Fusion Lumos |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2026-04-10 15:21:07 | ID requested | |
| ⏵ 1 | 2026-06-22 12:00:32 | announced | |
Publication List
Keyword List
| submitter keyword: FBXO7, Parkinson's Disease, Human,keywords: PI31, IP-MS |
Contact List
| J. Wade Harper |
|---|
| contact affiliation | Harvard Medical School Cell Biology Department |
| contact email | wade_harper@hms.harvard.edu |
| lab head | |
| Ellen Goodall |
|---|
| contact affiliation | Harvard Medical School |
| contact email | ellen_goodall@hms.harvard.edu |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/06/PXD077016 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD077016
- Label: PRIDE project
- Name: HAPI31-IP-MS, containing PI31 truncations and Parkinson's associated variants, with or without FBXO7
