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PXD076843-1

PXD076843 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitlePhosphatidylserine-Modified Self-Assembling Peptide Nanocarrier Enables Sustained FGF18 Delivery and Restores Mitochondrial Homeostasis for Cartilage Regeneration in Knee Osteoarthritis
DescriptionKnee osteoarthritis (KOA) remains a major clinical challenge due to the limited regenerative capacity of articular cartilage and the poor stability and bioavailability of therapeutic growth factors. In this study, we engineered a phosphatidylserine (PS)-modified RADA16-I self-assembling peptide nanocarrier for the encapsulation and sustained intra-articular delivery of fibroblast growth factor 18 (FGF18). Nuclear magnetic resonance (NMR)
HostingRepositoryiProX
AnnounceDate2026-04-09
AnnouncementXMLSubmission_2026-04-10_00:45:02.561.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterSihui Nie
SpeciesList scientific name: Rattus norvegicus; NCBI TaxID: 10116;
ModificationListNo PTMs are included in the dataset
InstrumentLTQ
Dataset History
RevisionDatetimeStatusChangeLog Entry
02026-04-10 00:43:37ID requested
12026-04-10 00:45:03announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Phosphatidylserine
Contact List
Jiawei Du
contact affiliationThe First Affiliated Hospital of Jinzhou Medical University
contact emaildjwfsyy123@163.com
lab head
Sihui Nie
contact affiliationThe first affiliated hospital of Jinzhou Medical University
contact email1545559471@qq.com
dataset submitter
Full Dataset Link List
iProX dataset URI