PXD076825-1

PXD076825 is an original dataset announced via ProteomeXchange.

Title	Proteomic analysis of myoglobin deficient adipose tissue
Description	This dataset contains mass spectrometry-based proteomics data from subcutaneous adipose tissue (SAT), visceral adipose tissue (VAT), and brown adipose tissue (BAT) isolated from wild-type and adipose-tissue-specific myoglobin knockout (ATMBKO) mice maintained at room temperature (23°C), thermoneutrality (30°C), or exposed to cold (8°C). The objective of the study was to determine the contribution of adipose myoglobin to thermogenesis and thermoregulation. The dataset provides a resource to investigate depot-specific and temperature-dependent proteomic changes associated with adipose myoglobin deficiency.
HostingRepository	PRIDE
AnnounceDate	2026-07-01
AnnouncementXML	Submission_2026-07-01_01:26:41.761.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Kristin Schubert
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: NEWT:10090;
ModificationList	No PTMs are included in the dataset
Instrument	quadrupole orbitrap astral instrument

Revision	Datetime	Status	ChangeLog Entry
0	2026-04-09 15:32:28	ID requested
⏵ 1	2026-07-01 01:26:42	announced

Strehlau C, Broghammer H, Gebhardt C, Hoffmann A, Hagemann T, Midilli Ş, Zimmer RS, Schubert K, Karagiannakou V, Georgiadi A, Ost M, Kr, ü, ger M, Roth L, Krause K, Kl, ö, ting N, Keller M, Wabitsch M, Nuwayhid R, Stimson RH, Stumvoll M, Bl, ü, her M, Weiner J, Heiker JT, Adipocyte Myoglobin Is a Determinant of Energy Expenditure and a Potential Target to Limit Obesity. Adv Sci (Weinh), ():e76191(2026) [pubmed]

10.1002/advs.76191;

submitter keyword: Myoglobin, thermogenesis, data-independent analysi, adipose tissue

Kristin Schubert
contact affiliation	Brandenburg University of Technology Cottbus-Senftenberg
contact email	kristin.schubert@b-tu.de
lab head
Kristin Schubert
contact affiliation	Brandenburg University of Technology Cottbus-Senftenberg
contact email	kristin.schubert@ufz.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/07/PXD076825

PRIDE project URI

• PRIDE
  1. PXD076825
     1. Label: PRIDE project
     2. Name: Proteomic analysis of myoglobin deficient adipose tissue