PXD076693 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Phosphopeptide mass spectrometry analysis of LATS2 identifies a second autophosphorylation site in HEK293A cells |
| Description | This dataset contains phosphopeptide LC-MS/MS data generated from human LATS2 overexpressed in HEK293A cells. The study was designed to identify LATS2 phosphorylation sites and to support phosphopeptide mapping of LATS2 autophosphorylation, with particular attention to the kinase-domain CLS site. Immunoprecipitated LATS2 samples were digested and analyzed by nanoLC-MS/MS. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-06-29 |
| AnnouncementXML | Submission_2026-06-28_16:27:25.807.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | 茹炘 靳 |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | phosphorylated residue |
| Instrument | timsTOF Pro |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2026-04-07 08:35:29 | ID requested | |
| ⏵ 1 | 2026-06-28 16:27:26 | announced | |
Publication List
| 10.1016/j.jbc.2026.113177; |
| Jin R, Zhong Z, Zhu R, Zhang A, Li J, Yu FX, Wang Y, LATS kinase activity and tumor suppressor function are regulated by a second autophosphorylation site. J Biol Chem, 302(7):113177(2026) [pubmed] |
Keyword List
| submitter keyword: Homo sapiens |
| HEK293A |
| LATS2 |
| Hippo pathway |
| autophosphorylation |
| phosphopeptide |
| LC-MS/MS |
| kinase |
Contact List
| Ruxin Jin |
|---|
| contact affiliation | Yu Faxiang Laboratory, Institute of Biomedical Sciences, Fudan University, Shanghai, China |
| contact email | 21111510016@m.fudan.edu.cn |
| lab head | |
| 茹炘 靳 |
|---|
| contact affiliation | No |
| contact email | 21111510016@m.fudan.edu.cn |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/06/PXD076693 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD076693
- Label: PRIDE project
- Name: Phosphopeptide mass spectrometry analysis of LATS2 identifies a second autophosphorylation site in HEK293A cells
