⮝ Full datasets listing
PXD076669-1
PXD076669 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Time- and Dose-Resolved DIA-PASEF Proteomics Maps the Transition from Adaptive Stress to Apoptotic Collapse in Melittin-Treated MDA-MB-231 Cells |
| Description | Label-free DIA-PASEF proteomics analysis of MDA-MB-231 triple-negative breast cancer cells treated with melittin at half IC50 and IC50 across multiple time points (0.5, 1, 2, 3, 4, 12, 24 h). Data were acquired on a Bruker timsTOF instrument. Raw data and processed outputs generated using Spectronaut are provided. The study investigates time- and dose-dependent proteomic responses, highlighting adaptive stress mechanisms at sublethal exposure and apoptotic commitment at cytotoxic doses. |
| HostingRepository | MassIVE |
| AnnounceDate | 2026-04-08 |
| AnnouncementXML | Submission_2026-04-08_07:28:45.739.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Non peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Clizia Chinello |
| SpeciesList | scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606; |
| ModificationList | Carbamidomethyl; N-acetylated residue |
| Instrument | timsTOF fleX |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2026-04-07 02:26:13 | ID requested | |
| ⏵ 1 | 2026-04-08 07:28:46 | announced |
Publication List
| no publication |
Keyword List
| submitter keyword: Melittin, Triple-negative breast cancer, DIA-PASEF proteomics, dose-dependent stress response, chromatin remodeling, cytoskeletal disassembly, apoptosis, DatasetType:Proteomics |
Contact List
| Clizia Chinello | |
|---|---|
| contact affiliation | UNIMIB |
| contact email | clizia.chinello@unimib.it |
| lab head | |
| Clizia Chinello | |
| contact affiliation | University of Milano Bicocca |
| contact email | clizia.chinello@unimib.it |
| dataset submitter | |
Full Dataset Link List
| MassIVE dataset URI |
| Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive-ftp.ucsd.edu/v12/MSV000101387/ |
