PXD076495 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Abundance analysis of chromatin-residing proteins during lineage conversion using protein aggregation capture (PAC) |
| Description | We performed abundance analysis of chromatin-residing proteins in BLaER1 cells during the early stages of B-cell-to-macrophage transdifferentiation. We employed protein aggregation capture (PAC) to analyze chromatin-residing protein abundances at 0, 6 and 24 h after induction of transdifferentiation in the absence and presence of the small-molecule SUMOylation inhibitor ML-792 (SUMOi). Mass spectrometry analyses were executed with high resolution mass spectrometry (LC-MS), using the Evosep One liquid chromatography system coupled to Orbitrap Astral mass spectrometer. Raw Orbitrap Astral data-independent acquisition (DIA) data were processed with DIA-NN. Data ouput from DIA-NN were further processed with ProteoGyver. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-05-27 |
| AnnouncementXML | Submission_2026-05-27_07:58:45.277.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Emma Valima |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | L-methionine removal; iodoacetamide derivatized residue |
| Instrument | quadrupole orbitrap astral instrument |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2026-04-02 02:51:52 | ID requested | |
| ⏵ 1 | 2026-05-27 07:58:45 | announced | |
Publication List
Keyword List
| submitter keyword: mass spectrometry, transdifferentiation,human, chromatin, BLaER1 |
Contact List
| Jorma J. Palvimo |
|---|
| contact affiliation | Institute of Biomedicine, University of Eastern Finland, Finland |
| contact email | jorma.palvimo@uef.fi |
| lab head | |
| Emma Valima |
|---|
| contact affiliation | Institute of Biomedicine, School of Medicine, University of Eastern Finland |
| contact email | emma.valima@uef.fi |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/05/PXD076495 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD076495
- Label: PRIDE project
- Name: Abundance analysis of chromatin-residing proteins during lineage conversion using protein aggregation capture (PAC)
