PXD076389 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Transferrin receptor 1 is a functional entry receptor for human parvovirus B19 |
| Description | Human parvovirus B19 (B19V) displays strict tropism for erythroid progenitor cells, governed by the VP1 unique region (VP1u), which mediates cell-specific uptake through interaction with an unknown cellular receptor. Proximity labeling in permissive erythroid cells identified transferrin receptor 1 (TfR1/CD71) as the predominant membrane protein associated with VP1u. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-09-07 |
| AnnouncementXML | Submission_2026-09-07_04:21:14.569.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Jan Bieri |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | biotinylated residue |
| Instrument | Q Exactive HF; Orbitrap Fusion Lumos |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2026-03-31 06:47:56 | ID requested | |
| ⏵ 1 | 2026-09-07 04:21:15 | announced | |
Publication List
| Lee H, Bieri J, Ammann N, Suter C, Hunziker D, Singh AK, Bator CM, Hafenstein SL, Ros C, Transferrin receptor 1 binds human parvovirus B19 VP1u to facilitate entry. Nat Commun, 17(1):(2026) [pubmed] |
| 10.1038/s41467-026-74283-7; |
Keyword List
| submitter keyword: receptor,B19V, MS, proximity labeling, TfR1 |
Contact List
| Carlos Ros |
|---|
| contact affiliation | Department of Chemistry, Biochemistry and Pharmaceutical Sciences, University of Bern, Switzerland. |
| contact email | carlos.ros@unibe.ch |
| lab head | |
| Jan Bieri |
|---|
| contact affiliation | University of Bern |
| contact email | jan.l.bieri@bluewin.ch |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/09/PXD076389 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD076389
- Label: PRIDE project
- Name: Transferrin receptor 1 is a functional entry receptor for human parvovirus B19
