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PXD076266-1

PXD076266 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProtein propionylation in Pcca deficiency
DescriptionTo determine the prevalence and identify any enrichment of lysine propionylation in PCC deficiency, an analysis comparing the propionylated liver proteins of control and liver-specific Pcca knockout mice was performed. Liver-specific knockout of PCC activity was induced in mice with floxed axons for the Pcca gene (Pcca ff) at 5 weeks of age using iCre-AAV with a TBG promoter. For controls, Pcca ff mice were injected with eGFP-AAV under the same promoter.
HostingRepositoryPRIDE
AnnounceDate2026-04-09
AnnouncementXMLSubmission_2026-04-09_06:55:53.083.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterJasmine Encarnacion
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: NEWT:10090;
ModificationListN6-propanoyl-L-lysine; monohydroxylated residue; iodoacetamide derivatized residue
InstrumentLTQ Orbitrap XL ETD
Dataset History
RevisionDatetimeStatusChangeLog Entry
02026-03-27 13:44:33ID requested
12026-04-09 06:55:53announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Mouse, Liver, Nano LC-MS/MS
Contact List
Michael J Wolfgang
contact affiliationDepartment of Physiology, Pharmacology and Therapeutics, The Johns Hopkins University School of Medicine, Baltimore, Maryland.
contact emailmwolfga1@jhmi.edu
lab head
Jasmine Encarnacion
contact affiliationJohns Hopkins University
contact emailjencarn3@jh.edu
dataset submitter
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Dataset FTP location
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PRIDE project URI
Repository Record List
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