PXD076266 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Protein propionylation in Pcca deficiency |
| Description | To determine the prevalence and identify any enrichment of lysine propionylation in PCC deficiency, an analysis comparing the propionylated liver proteins of control and liver-specific Pcca knockout mice was performed. Liver-specific knockout of PCC activity was induced in mice with floxed axons for the Pcca gene (Pcca ff) at 5 weeks of age using iCre-AAV with a TBG promoter. For controls, Pcca ff mice were injected with eGFP-AAV under the same promoter. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-04-09 |
| AnnouncementXML | Submission_2026-04-09_06:55:53.083.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Jasmine Encarnacion |
| SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: NEWT:10090; |
| ModificationList | N6-propanoyl-L-lysine; monohydroxylated residue; iodoacetamide derivatized residue |
| Instrument | LTQ Orbitrap XL ETD |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
| 0 | 2026-03-27 13:44:33 | ID requested | |
| ⏵ 1 | 2026-04-09 06:55:53 | announced | |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Mouse, Liver, Nano LC-MS/MS |
Contact List
| Michael J Wolfgang |
| contact affiliation | Department of Physiology, Pharmacology and Therapeutics, The Johns Hopkins University School of Medicine, Baltimore, Maryland. |
| contact email | mwolfga1@jhmi.edu |
| lab head | |
| Jasmine Encarnacion |
| contact affiliation | Johns Hopkins University |
| contact email | jencarn3@jh.edu |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
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| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD076266
- Label: PRIDE project
- Name: Protein propionylation in Pcca deficiency