PXD075803-1

PXD075803 is an original dataset announced via ProteomeXchange.

Title	TMT-based proteomic analysis of electroacupuncture and drug intervention in OVA-induced urticaria-like passive cutaneous anaphylaxis: rat model
Description	This project investigates protein expression changes in rat skin tissue following electroacupuncture (EA) treatment and positive drug intervention in an OVA-induced passive cutaneous anaphylaxis (PCA) urticaria-like model. A total of 12 skin samples were divided into 4 groups: Control (K), Model (M), EA treatment (X), and Positive drug control (Z), with 3 biological replicates per group. Proteins were labeled using TMT reagents and analyzed by LC-MS/MS (Q-Exactive). Differential expression analysis (FC>1.2, p<0.05) was performed for comparisons including M_vs_K, Z_vs_M, X_vs_M, and X_vs_Z.
HostingRepository	iProX
AnnounceDate	2026-03-18
AnnouncementXML	Submission_2026-06-03_17:54:55.598.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Linxin You
SpeciesList	scientific name: Rattus norvegicus; NCBI TaxID: 10116;
ModificationList	oxidation; S-carboxamidomethyl-L-cysteine
Instrument	Thermo Fisher Scientific instrument model

Revision	Datetime	Status	ChangeLog Entry
0	2026-03-18 02:01:36	ID requested
⏵ 1	2026-06-03 17:54:56	announced

Dataset with its publication pending

submitter keyword: TMT proteomics, rat skin, electroacupuncture, OVA-induced urticaria, passive cutaneous anaphylaxis, Western medicine control

Jiquan Li
contact affiliation	Liaoning University of Traditional Chinese Medicine, College of Acupuncture and Moxibustion
contact email	lnzy_zjtn_ljq@126.com
lab head
Linxin You
contact affiliation	Liaoning University Of Traditional Chinese Medicine
contact email	youlinxin282520@163.com
dataset submitter

iProX dataset URI