PXD075438 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Glycoproteomics of Human and Mouse Brains in Alzheimer’s Disease |
| Description | This study profiles glycoproteomic changes in human frontal cortex and mouse brain in Alzheimer’s disease models. We compare cognitively normal and AD human brain tissue, and wild-type and 5xFAD mouse brain, to define whether AD-associated hyperglycosylation reflects increased glycosylation of existing proteins. The work is integrated with spatial glycomics and related multiomic analyses to identify disease-associated glycopeptides and glycoproteins linked to neurodegeneration. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-03-31 |
| AnnouncementXML | Submission_2026-03-31_09:43:33.525.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | RAMON SUN |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | glycosylated residue |
| Instrument | LTQ Orbitrap |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2026-03-10 01:23:34 | ID requested | |
| ⏵ 1 | 2026-03-31 09:43:34 | announced | |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Alzheimer’s disease |
| glycoproteomics |
| N-glycosylation |
| human brain |
| mouse brain |
Contact List
| Ramon sun |
|---|
| contact affiliation | university of florida |
| contact email | ramonsun@ufl.edu |
| lab head | |
| RAMON SUN |
|---|
| contact affiliation | University of Florida |
| contact email | ramonsun@ufl.edu |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/03/PXD075438 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD075438
- Label: PRIDE project
- Name: Glycoproteomics of Human and Mouse Brains in Alzheimer’s Disease
