PXD075165 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Alpibectir–Ethionamide combination (AlpE) for the treatment of tuberculosis |
| Description | MS/MS data for profiling of Mycobacterium tuberculosis treated with Compound 1, Compound 2, Alpibectir, Compound 3 and vehicle control: 10 samples were analyzed in parallel (TMT 10-plex) to generate whole proteome profiling data. Mycobacterium tuberculosis were treated for 72h with 1µM of the respective compound: Samples 1 and 2 treated with Compound 1, samples 3 and 4 with Compound 2, samples 5 and 6 with Alpibectir, samples 7 and 8 with Compound 3 and samples 9 and 10 with DMSO (vehicle control experiments n=1 and n=2). |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-04-02 |
| AnnouncementXML | Submission_2026-04-01_23:20:30.597.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Sascha Knecht |
| SpeciesList | scientific name: Mycobacterium tuberculosis H37Rv; NCBI TaxID: NEWT:83332; |
| ModificationList | TMT6plex-126 reporter+balance reagent acylated residue; methionine oxidation with neutral loss of 64 Da; acetylated residue; iodoacetamide derivatized residue |
| Instrument | Q Exactive |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2026-03-03 15:10:57 | ID requested | |
| ⏵ 1 | 2026-04-01 23:20:31 | announced | |
Publication List
Keyword List
Contact List
| Thilo Werner |
|---|
| contact affiliation | Target Discovery, GSK / Cellzome |
| contact email | thilo.x.werner@gsk.com |
| lab head | |
| Sascha Knecht |
|---|
| contact affiliation | Target Discovery, GSK / Cellzome |
| contact email | sascha.knecht@me.com |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/04/PXD075165 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD075165
- Label: PRIDE project
- Name: Alpibectir–Ethionamide combination (AlpE) for the treatment of tuberculosis
