PXD075129 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Human proteomics analysis of BRD4 targeted small-molecules in KSHV+ cells by Orbitrap Eclipse and MaxQuant |
| Description | In this project, we used proteomics to identify and compare protein profile changed in SIM-1, MZ-1, or JQ-1 treated TIVE-LTC, a KSHV long-term infected immortalized endothelial cell line. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-06-08 |
| AnnouncementXML | Submission_2026-06-08_01:28:13.483.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Zhen Lin |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | LTQ Orbitrap Elite |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2026-03-02 20:41:02 | ID requested | |
| ⏵ 1 | 2026-06-08 01:28:14 | announced | |
Publication List
| 10.1371/journal.ppat.1014288; |
| Chen J, Fan J, Qin M, Lin Z, Mu S, Dai L, Qin Z, Targeting BRD2 and BRD4 inhibit the growth of KSHV-infected immortalized endothelial cells through suppression of LANA translation. PLoS Pathog, 22(6):e1014288(2026) [pubmed] |
Keyword List
| submitter keyword: BRD4, SIM-1,KSHV, MZ-1, JQ-1 |
Contact List
| Zhiqiang Qin |
|---|
| contact affiliation | Department of Pathology Winthrop P. Rockefeller Cancer Institute University of Arkansas for Medical Sciences |
| contact email | zqin@uams.edu |
| lab head | |
| Zhen Lin |
|---|
| contact affiliation | Tulane University |
| contact email | zlin@tulane.edu |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/06/PXD075129 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD075129
- Label: PRIDE project
- Name: Human proteomics analysis of BRD4 targeted small-molecules in KSHV+ cells by Orbitrap Eclipse and MaxQuant
