⮝ Full datasets listing
PXD074985-1
PXD074985 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Proteomic and metabolomic analysis of HPV-positive high grade squamous intraepithelial lesion |
| Description | Long-term exposure to high-risk human papilloma virus (HPV) leads to high grade squamous intraepithelial lesion (HSIL), which might develop into cancer. Various proteins and metabolites change during the development of cervical cancer, thus as-sessing the dysregulated molecules and pathways of HSIL is important to provide the diagnostic biomarkers. In proteomics analysis, 836 proteins showed significantly changes. Functional analyses of the differentially expressed proteins indicated that metabolic pathways, oxidative phosphorylation and ribosome are top three enriched pathways. |
| HostingRepository | iProX |
| AnnounceDate | 2026-02-27 |
| AnnouncementXML | Submission_2026-02-27_01:18:59.032.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Chengcheng Zhao |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive HF-X |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2026-02-27 01:18:32 | ID requested | |
| ⏵ 1 | 2026-02-27 01:18:59 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: HPV, High grade squamous intraepithelial lesion, Proteomics |
Contact List
| Jiangquan Chen | |
|---|---|
| contact affiliation | Nanjing Jiangning Hospital |
| contact email | jqchen@njmu.edu.cn |
| lab head | |
| Chengcheng Zhao | |
| contact affiliation | Nanjing Jiangning Hospital |
| contact email | zhao_chch@163.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
