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PXD074858-1

PXD074858 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteomic data of the perinatal pig brain
DescriptionThe uploaded proteome data were obtained from 336 samples of perinatal Bama miniature pigs, covering multiple time points and brain regions. Analyzed with transcriptome data, they revealed the spatiotemporal organization of perinatal molecular profiles and gene-protein expression concordance. These data helped confirm perinatal Bama miniature pigs as an optimal large-animal model for human perinatal neurodevelopment (closer to humans than mice). They also identified a pan-regional developmental inflection point (E94-E104) with dramatic changes in proteins related to synaptogenesis and gliogenesis, supported analyses of regional developmental heterogeneity, and facilitated studying brain disorder risk gene transitions, serving as a key part of the multi-omics atlas for decoding neurodevelopmental pathogenesis.
HostingRepositoryiProX
AnnounceDate2026-02-24
AnnouncementXMLSubmission_2026-02-24_23:29:24.421.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterZiming Wang
SpeciesList scientific name: Sus scrofa domesticus; NCBI TaxID: 9825;
ModificationListNo PTMs are included in the dataset
InstrumenttimsTOF HT
Dataset History
RevisionDatetimeStatusChangeLog Entry
02026-02-24 23:29:06ID requested
12026-02-24 23:29:24announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Proteomic Data, Bama miniature pig, Brain
Contact List
Mingfeng Li
contact affiliationHuazhong University of Science and Technology
contact emailmingfengli@hust.edu.cn
lab head
Ziming Wang
contact affiliationHuazhong University of Science and Technology
contact emailm202475814@hust.edu.cn
dataset submitter
Full Dataset Link List
iProX dataset URI