PXD074343 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Quantitative proteomic profiling of ruptured and unruptured brain arteriovenous malformations |
| Description | This study presents a quantitative proteomic analysis of human brain arteriovenous malformation (AVM) tissues with different rupture status. Surgically resected AVM specimens from ruptured and unruptured lesions were subjected to protein extraction, enzymatic digestion, and liquid chromatography–tandem mass spectrometry (LC-MS/MS) analysis. The dataset aims to characterize proteomic alterations associated with hemorrhagic presentation and to identify molecular pathways potentially involved in vascular instability. Raw mass spectrometry data and processed identification results are provided to facilitate data reuse and integrative multi-omics analyses. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-02-15 |
| AnnouncementXML | Submission_2026-02-14_17:13:44.103.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Wei Zhu |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | EASY-nLC 1200 |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2026-02-11 06:59:59 | ID requested | |
| ⏵ 1 | 2026-02-14 17:13:44 | announced | |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: proteomics, rupture status, vascular biology,Brain arteriovenous malformation, LC-MS/MS |
Contact List
| Wei Zhu |
|---|
| contact affiliation | Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University |
| contact email | drzhuwei@fdu.edu.cn |
| lab head | |
| Wei Zhu |
|---|
| contact affiliation | Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University |
| contact email | drzhuwei@fudan.edu.cn |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/02/PXD074343 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD074343
- Label: PRIDE project
- Name: Quantitative proteomic profiling of ruptured and unruptured brain arteriovenous malformations
