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PXD074161-1

PXD074161 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteomic Profiling of PTEN Inhibition on Periodontal Ligament Stem Cells
Description: Phosphatase and tensin homolog (PTEN) is a critical regulator of cell proliferation, differentiation, and inflammatory balance. However, its downstream proteomic effects in periodontal ligament stem cells (PDLSCs) remain poorly understood. This study aimed to elucidate the proteomic alterations induced by PTEN inhibition and identify potential molecular pathways underlying periodontal regeneration.
HostingRepositoryPRIDE
AnnounceDate2026-03-30
AnnouncementXMLSubmission_2026-03-29_16:06:42.747.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterSuphalak Phothichailert
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationListNo PTMs are included in the dataset
Instrumentautoflex
Dataset History
RevisionDatetimeStatusChangeLog Entry
02026-02-06 13:43:26ID requested
12026-03-29 16:06:43announced
Publication List
10.1016/j.identj.2026.109493;
Phothichailert S, Nowwarote N, Kornsuthisopon C, Murakami S, Srithanyarat SS, Osathanon T, Proteomic Profiling of PTEN Inhibition on Periodontal Ligament Stem Cells. Int Dent J, 76(3):109493(2026) [pubmed]
Keyword List
submitter keyword: Mesenchymal stem cells, VO-OHpic, Periodontal regeneration, MAPK cascade, Proteomics,PTEN inhibitor
Contact List
Suphalak Phothichailert
contact affiliationOral Biology (International Program), Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand
contact emailj.suphalak@gmail.com
lab head
Suphalak Phothichailert
contact affiliationOral biology
contact emailj.suphalak@gmail.com
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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