PXD074087 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | TMT-based proteome and phosphoproteome profiling of control and GPR146 knockdown SGBS cells |
| Description | This dataset contains quantitative proteome and phosphoproteome profiles of control and GPR146 knockdown SGBS human preadipocyte cells. Cells were processed for tandem mass tag (TMT)–based multiplexed quantitative mass spectrometry, with parallel analysis of total proteome input samples and TiO2-enriched phosphopeptides. The study aims to characterize global protein abundance and phosphorylation changes associated with GPR146 depletion. The dataset includes raw mass spectrometry files, processed identification and quantification results, and the protein sequence database used for analysis. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-02-23 |
| AnnouncementXML | Submission_2026-02-23_03:02:53.179.xml |
| DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD074087 |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Supported dataset by repository |
| PrimarySubmitter | Yu Shi |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | phosphorylated residue |
| Instrument | Orbitrap Fusion Lumos |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2026-02-05 06:02:17 | ID requested | |
| ⏵ 1 | 2026-02-23 03:02:53 | announced | |
Publication List
Keyword List
| submitter keyword: phosphoproteomics, GPR146, SGBS cells, Orbitrap, TMT6plex, LC-MS/MS |
Contact List
| Haojie Yu |
|---|
| contact affiliation | 1. Precision Medicine Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore. 2. Cardiovascular Disease Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore. 3. Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore. |
| contact email | bchhaoy@nus.edu.sg |
| lab head | |
| Yu Shi |
|---|
| contact affiliation | National University of Singapore |
| contact email | shiy8@nus.edu.sg |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/02/PXD074087 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD074087
- Label: PRIDE project
- Name: TMT-based proteome and phosphoproteome profiling of control and GPR146 knockdown SGBS cells
