⮝ Full datasets listing
PXD073899-1
PXD073899 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Calcium-mediated calreticulin IRE1α interaction drives dynamic fluctuation of IRE1α activity under chronic endoplasmic reticulum stress |
| Description | To investigate the mechanisms underlying fluctuating IRE1α phosphorylation under chronic endoplasmic reticulum stress, we performed co-immunoprecipitation coupled with mass spectrometry (IP-MS) to identify IRE1α-interacting proteins. Protein complexes were analyzed by LC-MS/MS, followed by bioinformatic enrichment analysis to identify candidate regulators of IRE1α phosphorylation and activity. |
| HostingRepository | iProX |
| AnnounceDate | 2026-01-30 |
| AnnouncementXML | Submission_2026-02-01_19:01:50.493.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Jianwei Cao |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Orbitrap Exploris 480 |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2026-02-01 19:01:26 | ID requested | |
| ⏵ 1 | 2026-02-01 19:01:50 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Endoplasmic reticulum stress, Unfolded protein response, IRE1α, Calreticulin, Calcium, and Chronic ER stress |
Contact List
| Likun Wang | |
|---|---|
| contact affiliation | Institute of Biophysics, Chinese Academy of Sciences |
| contact email | wanglikun@ibp.ac.cn |
| lab head | |
| Jianwei Cao | |
| contact affiliation | Institute of Biophysics, Chinese Academy of Sciences |
| contact email | caojianwei14@mails.ucas.ac.cn |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
