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PXD073759-1

PXD073759 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteomic analysis of HEK293T cells deficient in PRDX4 protein
DescriptionTo elucidate the regulatory network of PRDX4, we identified its interacting proteins through large-scale immunoprecipitation coupled with MS-based proteomics analysis. Notably, among the identified proteins, a E3 ubiquitin ligase ARIH1 potentially involved in PRDX4 degradation was enriched, with exhibiting the strongest interaction.
HostingRepositoryPRIDE
AnnounceDate2026-01-29
AnnouncementXMLSubmission_2026-01-29_06:29:02.197.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterYuqian Huo
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationListubiquitinylated lysine
InstrumenttimsTOF HT
Dataset History
RevisionDatetimeStatusChangeLog Entry
02026-01-29 02:33:35ID requested
12026-01-29 06:29:02announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: human
E3 ubiquitin ligases
PRDX4
proteomics
ubiquitination
Contact List
Xiaolan Liu
contact affiliationResearch Center of Clinical Pharmacy of The First Affiliated Hospital & Liangzhu Laboratory, Zhejiang University School of Medicine, Hangzhou, China.
contact email12018099@zju.edu.cn
lab head
Yuqian Huo
contact affiliationZhejiang University, Hangzhou, Zhejiang, China.
contact email12418129@zju.edu.cn
dataset submitter
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Dataset FTP location
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PRIDE project URI
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