PXD073758-1

PXD073758 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	DIA-MS based plasma peptidomics workflow for profiling organ-derived peptides
Description	In this study, we acquired DDA-MS data and DIA-MS data from peptide extracts of plasma and eleven organs (lung, spleen, adrenal gland, kidney, heart, liver, muscle, pancreas, cerebellum, hippocampus, and cerebral cortex). These data were analyzed using FragPipe v23 to obtain peptide identification results and to construct an empirical spectral library. We also acquired DIA-MS data from plasma peptide extracts and analyzed them with DIA-NN v2.3.1 using three empirical spectral libraries that we constructed, thereby obtaining peptide identification results.
HostingRepository	jPOST
AnnounceDate	2026-07-13
AnnouncementXML	Submission_2026-07-12_22:31:06.958.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yusei Okuda
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	2-pyrrolidone-5-carboxylic acid (Gln); 2-pyrrolidone-5-carboxylic acid (Glu); unknown modification; L-methionine sulfoxide; alpha-amino acetylated residue; Amidated
Instrument	timsTOF HT

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2026-01-29 01:16:39	ID requested
⏵ 1	2026-07-12 22:31:07	announced

Publication List

Okuda Y, Konno R, Taguchi T, Itakura M, Tamari A, Matsui T, Miyatsuka T, Ohara O, Kawashima Y, Kodera Y, Organ-Derived Spectral Libraries Improve Sensitivity in DIA Plasma Peptidomics. Proteomics, ():e70165(2026) [pubmed]

Okuda Y, Konno R, Taguchi T, Itakura M, Tamari A, Matsui T, Miyatsuka T, Ohara O, Kawashima Y, Kodera Y, Organ-Derived Spectral Libraries Improve Sensitivity in DIA Plasma Peptidomics. Proteomics, ():e70165(2026) [pubmed]

Keyword List

submitter keyword: peptidomics, peptidome, DIA-MS, mouse, plasma, organs

submitter keyword: peptidomics, peptidome, DIA-MS, mouse, plasma, organs

Contact List

Yoshio Kodera
lab head
Yusei Okuda
contact affiliation	Kitasato University
dataset submitter

Full Dataset Link List

jPOST dataset URI
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jPOST dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST003835/