PXD073574 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Investigation of PSMA3 in brains of B6 mice |
| Description | The PSMA3 (Proteasome subunit alpha type-3) protein was identified by ligand affinity chromatography in brain specimens (frontal cortex and hippocampus) of 6-month-old, non-transgenic B6 mice, as a protein which interacts with CPD57 (4-(4-fluorophenyl)-6-(hydroxymethyl)-2-methyl-pyridine-3-carboxamide). Proteins from brain specimens were solubilized and subjected to ligand affinity chromatography applying an affinity matrix with covalently coupled CPD57. After overnight incubation at 4 °C and washing steps to remove unbound proteins, bound proteins were eluted from the ligand affinity matrix and separated by SDS-PAGE. The ligand affinity matrix with covalently coupled CPD57 enriched a protein in the range of 25-30 kDa. The protein band was cut out and subjected to identification by nano-LC-ESI-MS/MS. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-02-16 |
| AnnouncementXML | Submission_2026-02-16_14:22:15.039.xml |
| DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD073574 |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Supported dataset by repository |
| PrimarySubmitter | Ursula Quitterer |
| SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: NEWT:10090; |
| ModificationList | monohydroxylated residue; deamidated residue; iodoacetamide derivatized residue |
| Instrument | LTQ Orbitrap Velos |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2026-01-26 08:58:52 | ID requested | |
| ⏵ 1 | 2026-02-16 14:22:15 | announced | |
Publication List
Keyword List
| submitter keyword: frontal cortex,PSMA3, B6 mouse, brain, hippocampus |
Contact List
| Prof. Dr. Ursula Quitterer |
|---|
| contact affiliation | Molecular Pharmacology, ETH Zurich, Switzerland |
| contact email | ursula.quitterer@pharma.ethz.ch |
| lab head | |
| Ursula Quitterer |
|---|
| contact affiliation | ETH Zurich |
| contact email | ursula.quitterer@pharma.ethz.ch |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
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| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD073574
- Label: PRIDE project
- Name: Investigation of PSMA3 in brains of B6 mice
