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PXD073186-1

PXD073186 is an original dataset announced via ProteomeXchange.

Dataset Summary
Titlehuman endothelial brain cells, human astrocytes , huma neurons- mass spectrometry quantification of exosomes and corresponding cell
DescriptionThis study characterizes the EV-derived proteome secreted by three major cell types of the neurovascular unit: human brain endothelial cells (HBECs), astrocytes, and neurons. Mass spectrometry analyses of EVs and corresponding cells were performed to assess the functional roles of EVs in brain intercellular communication. This study characterizes the EV-derived proteome secreted by three major cell types of the neurovascular unit: human brain endothelial cells (HBECs), astrocytes, and neurons. Mass spectrometry analyses of EVs and corresponding cells were performed to assess the functional roles of EVs in brain intercellular communication.
HostingRepositoryPRIDE
AnnounceDate2026-06-08
AnnouncementXMLSubmission_2026-06-07_16:17:37.908.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterGergana Nestorova
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationListNo PTMs are included in the dataset
InstrumenttimsTOF Pro
Dataset History
RevisionDatetimeStatusChangeLog Entry
02026-01-17 01:35:13ID requested
12026-06-07 16:17:38announced
Publication List
10.3390/proteomes14020024;
Hutson HK, Qin G, Cai C, Nestorova GG, Cell Type-Specific Proteomic Cargo in Human Brain Endothelial, Astrocyte, and Neuronal Extracellular Vesicles. Proteomes, 14(2):(2026) [pubmed]
Keyword List
submitter keyword: astrocytes, neurons,exosomes, endothelial brain cells
Contact List
Dr.Gergana G. Nestorova
contact affiliationLouisiana Tech University School of Biological Sciences 1 Adams Blvd. Ruston, LA, 71272
contact emailggnestor@latech.edu
lab head
Gergana Nestorova
contact affiliationLouisiana Tech University
contact emailggnestor@latech.edu
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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