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PXD072889-1

PXD072889 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleNuclear proteome map of mouse heart chamber
DescriptionHeart specialisation involves nuclear programs however chamber-specific regulation of the nuclear proteome landscape remains unknown. In this study we isolated the nucleus from four major anatomical regions of healthy mouse heart (fresh) and employed quantitative mass spectrometry-based proteomics DIA-MS to construct a comprehensive nuclear proteome landscape. We also define a set of 932 proteins that were highly conserved across all anatomical regions, including transcription-regulator complexes, nucleolar/ribosome-associated, RNA-processing, and chromatin-organization components
HostingRepositoryMassIVE
AnnounceDate2026-01-11
AnnouncementXMLSubmission_2026-01-11_03:10:59.977.xml
DigitalObjectIdentifier
ReviewLevelNon peer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterDavid Greening
SpeciesList scientific name: Mus musculus; common name: house mouse; NCBI TaxID: 10090;
ModificationListAcetyl
InstrumentQ Exactive HF-X
Dataset History
RevisionDatetimeStatusChangeLog Entry
02026-01-10 20:17:12ID requested
12026-01-11 03:11:00announced
Publication List
no publication
Keyword List
submitter keyword: heart, nucleus, subcellular, heart regions, transcription factors, DatasetType:Proteomics
Contact List
David Greening
contact affiliationBaker Heart & Diabetes Institute
contact emaildavid.greening@baker.edu.au
lab head
David Greening
contact affiliationBaker Heart & Diabetes Institute
contact emaildavid.greening@baker.edu.au
dataset submitter
Full Dataset Link List
MassIVE dataset URI
Dataset FTP location
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