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PXD072867-1

PXD072867 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleDIA-PASEF Proteomic Analysis of Metabolic Responses to Amino Acid Supplementation in H441 Cells
DescriptionThis dataset contains untargeted proteomic measurements from H441 epithelial cells cultured under physiologic metabolic conditions. Cells were conditioned in human plasma–like medium (HPLM) and treated with or without an amino acid supplement. Proteomic profiling was performed to quantify global protein abundance changes associated with amino acid supplementation under these metabolic conditions. Pathway-level analyses were conducted to characterize cellular processes altered by supplementation. This dataset provides a resource for examining proteome-level responses to metabolic modulation in epithelial cells.
HostingRepositoryPRIDE
AnnounceDate2026-03-11
AnnouncementXMLSubmission_2026-03-11_16:32:59.716.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterRyan McClure
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationListacetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
InstrumenttimsTOF Ultra 2
Dataset History
RevisionDatetimeStatusChangeLog Entry
02026-01-09 14:30:48ID requested
12026-03-11 16:33:00announced
Publication List
10.1126/SCITRANSLMED.ADX4097;
Keyword List
submitter keyword: Human, timsTOF Ultra 2, LCMS
Contact List
Ryan McClure
contact affiliationMS Omics, Biohub Chicago, USA
contact emailryan.mcclure@biohub.org
lab head
Ryan McClure
contact affiliationBiohub Chicago
contact emailryan.mcclure@biohub.org
dataset submitter
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Dataset FTP location
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