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PXD072432-1

PXD072432 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleStiffness influences the secretion of TSPCs
DescriptionIn this study, we found that tendon stiffness increased following injury in a rat tendon injury model, indicating the potential effect of stiffness on tendon regeneration. Then, we collected the conditioned medium (CM) of TSPCs cultured on matrices with different stiffnesses, and cultured TSPCs and macrophages with CM to evaluate the impact of stiffness on intercellular communications within tendon. Mass spectrometry-based proteomics and secretomes were performed to discern the underlying mechanism of the stiffness regulating intercellular crosstalks.
HostingRepositoryiProX
AnnounceDate2025-12-26
AnnouncementXMLSubmission_2026-08-31_20:12:01.720.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterChuan Quan
SpeciesList scientific name: Rattus norvegicus; NCBI TaxID: 10116;
ModificationListNo PTMs are included in the dataset
InstrumentOrbitrap Fusion Lumos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-12-25 22:20:34ID requested
12026-08-31 20:12:02announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: secretion, tendon
Contact List
Jialin Chen
contact affiliationSoutheast University
contact emailjialin.chen@seu.edu.cn
lab head
Chuan Quan
contact affiliationSoutheast University
contact email230248598@seu.edu.cn
dataset submitter
Full Dataset Link List
iProX dataset URI