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PXD072416-1

PXD072416 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Defective O-fucosylation of EDIL3 attenuates invasion and vascular remodeling of trophoblasts via LIFR signaling pathway in preeclampsia
Description	Preeclampsia(PE)is a severe placental disorder that affects 3%-5% of all pregnancies worldwide. The primary cause of PE is abnormal placentationduring eanly pregnancy, including poor trophoblast invasion and insutficientapiral arteriole remodeling, Protein O-ucosylation is a type of protein posttranslational modification that is catalyzed by Protein O-fucosy'ltransferase(poFUT). However, the role and underlying mechanisms of protein O-fucosylation and poFUT1 in PE remain elusive.
HostingRepository	iProX
AnnounceDate	2025-12-25
AnnouncementXML	Submission_2025-12-24_22:57:17.437.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yubo Liu
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Fusion

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-12-24 22:57:03	ID requested
⏵ 1	2025-12-24 22:57:17	announced

Publication List

Dataset with its publication pending

Keyword List

submitter keyword: O-fucosylation, EDIL3, preeclampsia

Contact List

Shuai Liu
contact affiliation	Dalian Medical University
contact email	liushuai@dmu.edu.cn
lab head
Yubo Liu
contact affiliation	Northeastern University
contact email	liuyubo@neu.edu.cn
dataset submitter

Full Dataset Link List

iProX dataset URI