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PXD072252-1

PXD072252 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteomic analysis of redox PTMs in HCoV-229E-infected immortalized human lung fibroblasts (MRC5)
DescriptionTMT18-labeled proteome-wide profiling of post-translational modifications (redox) in mock-infected and infected human lung epithelial cells (MRC5). Human lung epithelial (MRC5) cells were infected and mock-infected with HCoV-229E. Cells were harvested at 8, 16, and 24 hours post-infection. Extracted proteins were digested with trypsin, then TMT18-labeled and enriched for redox PTMs. Samples were split into 12 fractions and run on the Q Exactive Plus. Data was searched with MS-GF+ using PNNL's DMS Processing pipeline.
HostingRepositoryMassIVE
AnnounceDate2025-12-24
AnnouncementXMLSubmission_2025-12-24_16:56:39.097.xml
DigitalObjectIdentifier
ReviewLevelNon peer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterMatthew Monroe
SpeciesList scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606; scientific name: Human coronavirus 229E; NCBI TaxID: 11137;
ModificationListOxidation; Carbamidomethyl; Nethylmaleimide; TMTpro
InstrumentQ Exactive Plus
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-12-20 21:14:01ID requested
12025-12-24 16:56:39announced
Publication List
no publication
Keyword List
submitter keyword: HCoV-229E, coronavirus, human lung, post-translational modifications, redox, DatasetType:Proteomics
Contact List
Tong Zhang
contact affiliationPacific Northwest National Laboratory
contact emailtong.zhang@pnnl.gov
lab head
Amy Sims
contact affiliationPacific Northwest National Laboratory
contact emailamy.sims@pnnl.gov
lab head
Matthew Monroe
contact affiliationPacific Northwest National Laboratory
contact emailmatthew.monroe@pnnl.gov
dataset submitter
Full Dataset Link List
MassIVE dataset URI
Dataset FTP location
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