⮝ Full datasets listing
PXD071925-1
PXD071925 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Proteome-based identification and validation of NXPE3 in childhood acute lymphoblastic leukaemia |
| Description | Background: Acute lymphoblastic leukaemia (ALL) is the most common cancer in children. Proteomics, supported by mass spectrometry and bioinformatics, investigates cancer biology and contributes to translational research. Purpose of the study: To identify the plasma proteome profile of children across different risk groups of ALL. Neurexophilin and PC-esterase family, member 3 (NXPE3), was validated. The protein-protein interactions (PPI) of NXPE3 were evaluated with bioinformatics analyses. Material and methods: Plasma samples from 15 patients with B-ALL standard risk (SR), B-ALL high risk (HR), and T-ALL high risk (HR), were analyzed using liquid chromatography with tandem mass spectrometry. NXPE3 protein was validated using ELISA. To compare the NXPE3 values across groups, the Kruskal-Wallis test was applied. A p-value < 0.05 was considered significant. STRING database was used for PPI. |
| HostingRepository | MassIVE |
| AnnounceDate | 2025-12-12 |
| AnnouncementXML | Submission_2025-12-12_13:37:43.483.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Non peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | basir syed |
| SpeciesList | scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606; |
| ModificationList | S-carboxamidomethyl-L-cysteine |
| Instrument | impact II |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2025-12-12 12:21:16 | ID requested | |
| ⏵ 1 | 2025-12-12 13:37:43 | announced |
Publication List
| no publication |
Keyword List
| submitter keyword: Acute lymphoblastic leukaemia, Mass spectrometry, Proteomics, DatasetType:Proteomics |
Contact List
| Ahmad Syed | |
|---|---|
| contact affiliation | Chapman University |
| contact email | aahmed@chapman.edu |
| lab head | |
| basir syed | |
| contact affiliation | chapman university |
| contact email | bsyed@chapman.edu |
| dataset submitter | |
Full Dataset Link List
| MassIVE dataset URI |
| Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive-ftp.ucsd.edu/v11/MSV000100202/ |
