PXD071869 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Multi‑instrument DIA proteomics of Escherichia coli and Halomonas bluephagenesis TD01 ratio mixtures for biomanufacturing‑relevant instrument comparison |
| Description | This project benchmarks five DIA-based LC–MS platforms for their ability to quantify proteins in E. coli and Halomonas bluephagenesis under biomanufacturing‑relevant conditions. Using simple peptide ratio mixtures and an exemplar carbon source comparison, it shows how instruments across a range of costs can still deliver actionable coverage of core metabolic pathways. The work is aimed at positioning quantitative proteomics as a practical tool for chassis selection, process development, and troubleshooting in industrial biomanufacturing. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-01-11 |
| AnnouncementXML | Submission_2026-01-11_15:13:53.923.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Matthew Russell |
| SpeciesList | scientific name: Escherichia coli; NCBI TaxID: NEWT:562; scientific name: Halomonas bluephagenesis; NCBI TaxID: NEWT:2778948; |
| ModificationList | monohydroxylated residue; iodoacetamide derivatized residue |
| Instrument | ZenoTOF 7600; Waters instrument model; Orbitrap Exploris 480 |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-12-11 05:00:30 | ID requested | |
| ⏵ 1 | 2026-01-11 15:13:54 | announced | |
Publication List
Keyword List
| submitter keyword: data‑independent acquisition (DIA), LC‑MS, engineered biology, biomanufacturing, DIA‑NN / DIANN, SWATH‑MS, process monitoring,quantitative proteomics, MSstats., process control |
Contact List
| Nigel Scrutton |
|---|
| contact affiliation | Professor and Director of UK Future Biomanufacturing Research Hub |
| contact email | nigel.scrutton@manchester.ac.uk |
| lab head | |
| Matthew Russell |
|---|
| contact affiliation | University of Manchester |
| contact email | russell.matthew.r@gmail.com |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/01/PXD071869 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD071869
- Label: PRIDE project
- Name: Multi‑instrument DIA proteomics of Escherichia coli and Halomonas bluephagenesis TD01 ratio mixtures for biomanufacturing‑relevant instrument comparison
