PXD071855-1

PXD071855 is an original dataset announced via ProteomeXchange.

Title	DIA Proteomics Unveils cAMP and HPT Axis in Hu Sheep Spermatogenesis
Description	Reproductive efficiency in sheep is critically important for livestock production. This study provides the first multi-tissue proteomic characterization of high fecundity in Hu sheep, suggesting that their reproductive superiority may originate from hypothalamic-driven regulation, efficient coordination of key signaling pathways such as cAMP, and complex interactions among functionally important proteins across tissues. These findings offer valuable molecular insights into the regulation of reproductive traits in sheep, and the identified key proteins and pathways represent promising targets for further functional validation and molecular breeding applications.
HostingRepository	iProX
AnnounceDate	2025-12-11
AnnouncementXML	Submission_2025-12-11_00:08:53.175.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Lina Zhu
SpeciesList	scientific name: Ovis; NCBI TaxID: 9935;
ModificationList	Applied Biosystems iTRAQ(TM) multiplexed quantitation chemistry
Instrument	timsTOF Pro

Revision	Datetime	Status	ChangeLog Entry
0	2025-12-11 00:08:05	ID requested
⏵ 1	2025-12-11 00:08:53	announced

Dataset with its publication pending

submitter keyword: Sheep

Proteomics

Hypothalamic-pituitary-testicular axis

Differentially expressed proteins

Yaojing Yue
contact affiliation	Chinese Academy of Agricultural Sciences Lanzhou Institute of Animal Husbandry and Veterinary Medicine
contact email	yueyaojing@caas.cn
lab head
Lina Zhu
contact affiliation	Lanzhou Institute of Husbandry and Pharmaceutical Sciences
contact email	19530465839@139.com
dataset submitter

iProX dataset URI