⮝ Full datasets listing
PXD071841-1
PXD071841 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Proteomic profiling of human circulating endothelial cells in sepsis using nanoproteomics |
| Description | Circulating endothelial cells (CECs) are shed from the vascular intima into the bloodstream during endothelial injury and serve as a minimally invasive indicator of vascular dysfunction in sepsis. In this study, we isolated CECs from peripheral blood samples of patients with sepsis and healthy donors using high-dimensional spectral flow cytometry (Hoechst⁺/7-AAD⁻/CD45⁻/CD34⁺/CD146⁺). Due to the extremely low abundance of CECs in circulation, a nanoproteomics workflow optimized for trace cellular protein profiling was applied. |
| HostingRepository | iProX |
| AnnounceDate | 2025-12-11 |
| AnnouncementXML | Submission_2025-12-10_18:09:55.200.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Junping Kou |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Orbitrap Fusion |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2025-12-10 18:09:40 | ID requested | |
| ⏵ 1 | 2025-12-10 18:09:55 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: circulating endothelial cells, nanoproteomics, sepsis |
Contact List
| Junping Kou | |
|---|---|
| contact affiliation | China Pharmaceutical University |
| contact email | junpingkou@cpu.edu.cn |
| lab head | |
| Junping Kou | |
| contact affiliation | China Pharmaceutical University |
| contact email | junpingkou@cpu.edu.cn |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
