PXD071598-1

PXD071598 is an original dataset announced via ProteomeXchange.

Title	Primary human cholangiocytes treated with degrader Compound X
Description	Primary human cholangiocytes, sourced from one of three vendors (DDA experiment: ABM or Creative Bioarray; DIA experiment: ScienCell), were plated to 200,000 cells per replicate/condition in a 6-well plate, and then treated for 18 hours with heterobifunctional degrader Compound X (DDA: 0, 1, or 10 uM; DIA: 0, 0.3, 1, or 3 uM). They were then harvested and proteomes quantified. DOI 10.3389/fphar.2025.1664889
HostingRepository	PRIDE
AnnounceDate	2025-12-05
AnnouncementXML	Submission_2025-12-04_18:35:23.147.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	James Kath
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationList	acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2025-12-04 16:40:09	ID requested
⏵ 1	2025-12-04 18:35:23	announced

10.3389/FPHAR.2025.1664889;

submitter keyword: None

James Kath
contact affiliation	AbbVie, Inc.
contact email	james.kath@abbvie.com
lab head
James Kath
contact affiliation	AbbVie, Inc.
contact email	james.kath@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/12/PXD071598

PRIDE project URI

• PRIDE
  1. PXD071598
     1. Label: PRIDE project
     2. Name: Primary human cholangiocytes treated with degrader Compound X