⮝ Full datasets listing
PXD071397-1
PXD071397 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | APOE4 drives widespread changes to the hepatic proteome and alters metabolic function |
| Description | Unbiased data independent acquisition (DIA) proteomic analysis on APOE3 and APOE4 targeted replacement mice whole livers, isolated liver mitochondria, and APOE3 and APOE4 human iPSC derived hepatocyte like cells (iHLCs). Protein samples were extracted using chloroform/methanol phase separation with a subsequent trypsin digestion to acquire peptides. Samples were analyzed using liquid chromatography mass spectrometry (LC/MS) on a Orbitrap Exploris 480 (Thermo Scientific). |
| HostingRepository | MassIVE |
| AnnounceDate | 2026-01-05 |
| AnnouncementXML | Submission_2026-01-05_09:03:40.014.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Non peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Colton Lysaker |
| SpeciesList | scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606; scientific name: Mus musculus; common name: house mouse; NCBI TaxID: 10090; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Orbitrap Exploris 480 |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2025-11-30 10:19:45 | ID requested | |
| ⏵ 1 | 2026-01-05 09:03:40 | announced |
Publication List
| no publication |
Keyword List
| submitter keyword: Liver, Hepatocyte, iHLC, Mitochondria, APOE, DatasetType:Proteomics |
Contact List
| Heather Wilkins | |
|---|---|
| contact affiliation | University of Kansas Medical Center |
| contact email | hwilkins@kumc.edu |
| lab head | |
| Colton Lysaker | |
| contact affiliation | University of Kentucky |
| contact email | C.Lysaker@uky.edu |
| dataset submitter | |
Full Dataset Link List
| MassIVE dataset URI |
| Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive-ftp.ucsd.edu/v11/MSV000100053/ |
