⮝ Full datasets listing
PXD071300-1
PXD071300 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Self-polymerized Polyphenol-based Platform for the Management of Dry Eye Pathogenesis |
| Description | A polyphenol-based eye drop is developed via the self-polymerization of rosmarinic acid in the presence hyaluronic acid, followed by co-assembly with cerium ions to afford monodispersed RHC NPs. To enhance the ocular retention efficiency, thiol groups are further decorated on NPs (termed as s-RHC NPs). In two mouse models of DED, topical administration of s-RHC NPs leads to comprehensive relief of symptoms, including inflammatory response suppression, corneal epithelial defect repair, and tear secretion recovery. |
| HostingRepository | iProX |
| AnnounceDate | 2025-11-27 |
| AnnouncementXML | Submission_2026-01-26_00:50:24.428.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Zixin Wang |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive HF |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2025-11-26 23:32:37 | ID requested | |
| ⏵ 1 | 2026-01-26 00:50:24 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Polymerization, dry eye disease, mucin, polyphenol |
Contact List
| Yin Wang | |
|---|---|
| contact affiliation | Shanghai Jiao Tong UniversityLab Headla |
| contact email | yinwang@sjtu.edu.cn |
| lab head | |
| Zixin Wang | |
| contact affiliation | Shanghai Jiao Tong University |
| contact email | wangzixin0115@sjtu.edu.cn |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
