⮝ Full datasets listing
PXD071244-1
PXD071244 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Inhibition of FTO suppresses the proliferation of sCLc in a YTHDF2-dependent manner |
| Description | This study investigates the role of the fat mass and obesity-associated protein(FTO)，an m6A RNA demethylase,in small cell lung cancer(SCLC).LC-MS sequencing was performed to evaluate the protein changes in SCLC cell lines H69 and H82 following treatment with the selective FTO inhibitors， FB23-2. Cells were treated with the inhibitors under defined conditions . The resulting dataset provides valuable insight into the downstream molecular effects ofFTO inhibition in SCLC and may contribute to the identification of potential therapeutic targets in this highly aggressive tumor type. |
| HostingRepository | iProX |
| AnnounceDate | 2025-11-26 |
| AnnouncementXML | Submission_2025-11-25_19:44:57.501.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Feifeng Zhu |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive HF-X |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2025-11-25 19:43:18 | ID requested | |
| ⏵ 1 | 2025-11-25 19:44:58 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: FTO , YTHDF2 |
Contact List
| Huasong Lu | |
|---|---|
| contact affiliation | Life Sciences Institute, Zhejiang University |
| contact email | huasong_lu@zju.edu.cn |
| lab head | |
| Feifeng Zhu | |
| contact affiliation | zhejiang University |
| contact email | 18389247918@163.COM |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
