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PXD071140-1

PXD071140 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleHormone-dependent secretome profiling of bovine oviductal epithelial organoids
DescriptionThis project characterizes the hormone-dependent secretome of bovine oviductal epithelial organoids. Organoids were stimulated with estradiol or progesterone to mimic follicular and luteal phases, and their secretions were analyzed by LC-MS/MS. The resulting proteomic profiles closely matched native oviductal fluid and revealed clear endocrine-specific signatures, demonstrating that organoids faithfully reproduce the molecular and secretory landscape of the bovine oviduct.
HostingRepositoryPRIDE
AnnounceDate2026-06-01
AnnouncementXMLSubmission_2026-05-31_16:25:17.121.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterSergio Navarro
SpeciesList scientific name: Bos taurus (Bovine); NCBI TaxID: NEWT:9913;
ModificationListNo PTMs are included in the dataset
InstrumenttimsTOF fleX
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-11-24 12:06:45ID requested
12026-05-31 16:25:17announced
Publication List
10.1007/s00018-026-06200-6;
Navarro-Serna S, Romero-Aguirregomezcorta J, Hern, á, ndez-D, í, az N, Ferrero-Mic, ó A, Coy P, P, é, rez-Garc, í, a V, Hormonally responsive bovine oviductal organoids recapitulate native oviductal secretions and enhance sperm capacitation. Cell Mol Life Sci, 83(1):(2026) [pubmed]
Keyword List
submitter keyword: oviductal fluid, secretion, bovine,Organoids, oviduct, cow, epithelial cells
Contact List
Vicente Perez-Garcia
contact affiliationCentro de Biología Molecular (CBM)
contact emailvperez@cbm.csic.es
lab head
Sergio Navarro
contact affiliationCentro de Biología Molecular (CBM)
contact emailsergio.navarro@cbm.csic.es
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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